HPLC Column, HPS Silica, 5um, 4.6mm ID x 150mm Length, 120A. Cogent Brand. 1 EA.
Additional Info:
75001-15P Cogent HPS Silica™ HPLC Column is packed with high‑purity, unmodified silica, delivering reliable and reproducible performance for normal phase chromatography and USP L3 classified methods.
This stationary phase is not chemically bonded, allowing strong, direct interactions with polar and hydrophilic compounds, making it especially suitable for fats, lipids, and other polar analytes.
This very popular HPS Silica™ phase has been widely used in analytical laboratories for many years as a premium-value, dependable alternative to traditional silica columns such as Inertsil® and Luna®, providing consistent retention and selectivity.
With a 5 µm particle size, this column offers a balance of efficiency and robustness, allowing higher flow rates with lower backpressure, making it ideal for routine and advanced analytical applications on standard HPLC systems.
150 mm Length – Maximum Resolution for Normal Phase HPLC
The 150 mm length provides enhanced resolving power for complex separations.
Higher resolution than 50 mm and 100 mm columns
Improved separation of closely related compounds
Increased peak capacity for complex mixtures
✅ Recommended for applications requiring maximum resolution and separation depth
4.6 mm ID – Standard Analytical Format
Designed for 4.6 mm ID analytical columns
Fully compatible with standard HPLC systems
Higher sample loading capacity
Ideal for routine analysis and QC workflows
✅ Recommended for general analytical use and compendial methods
Flow Rate & System Requirements (4.6 mm ID, 5 µm)
✅ Compatible with standard HPLC systems
Typical flow rate range: ~1.0 – 1.5 mL/min
Lower backpressure compared to smaller particle columns
Suitable for routine normal phase separations
Compatible with UV and other standard detectors
✅ Best Practice: Optimize mobile phase conditions to maintain reproducible retention in normal phase
Why Choose HPS Silica™ Columns
High‑Purity Unmodified Silica
Ideal for normal phase chromatography
Strong retention for polar compounds
USP L3 Compatibility
Suitable for compendial methods
Reliable alternative to established silica columns
Proven Popularity & Reliability
Widely used across HPLC labs
Consistent performance over time
Performance Advantages
Lower Backpressure (5 µm Particles)
Allows higher flow rates
Compatible with conventional HPLC systems
Fast Equilibration
Reduces downtime between runs
Effective Polar Retention
Ideal for hydrophilic compounds, fats, and lipids
Typical Applications
Fats and lipid analysis
High‑resolution normal phase separations
Polar compound analysis
USP L3 methods
Food, pharmaceutical, and chemical workflows
Important Usage Notes
Designed for normal phase chromatography conditions
Use appropriate non‑polar mobile phases
Ensure proper system equilibration before analysis
Follow standard silica column handling practices